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Pairwise comparisons of these six assemblies suggested that assemblies produced by the same assembler were more similar to each other.
Assemblies produced by the same assembler were covered more frequently by each other.
Similar(58)
Comparisons between the performance of the same assembler in different species are confounded by the different nature of the input sequence data that was provided for each species.
By contrast, the virtues of the authors' assembler are that each product is made in one flask, without the need for purification steps after each assembly step; and that each of the four products can be made efficiently using the same assembler, rather than in separate synthetic routes that each need individual optimization to produce good yields.
These self-corrected, PacBio-only reads can be fed into the same assemblers as the hybrid reads.
To eliminate erroneously assembled transcripts, we applied a stringent criteria [ 28, 29] to identify probable transcripts which should be detected by two assemblers in same sample or identified in at least two individual samples by same assembler and defined a set of 235,283 cleavage stage transcripts.
By the same back.
cut by the same endonucleases.
This is evident by the fact that despite using the same input, different assemblers can produce draft assemblies that differ considerably in size and error rates.
List of reads excluded from the assembly by the Arachne assembler and the reported reason for their exclusion.
Second, the preprocessed data for each individual pool were assembled by the Newbler assembler from 454/Roche.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com