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In clinics using new microscopy, 37% (75/202) of patients who were negative by the reference slide received a malaria drug and 60% (103/202) received an antibiotic.
In clinics using established microscopy, 50.8% (645/1269) of patients who were negative by the reference slide received a malaria drug and 27.0% (342/1269) received an antibiotic.
The distribution of the different tissues matches with the result of Fig. 3(b) and both results are finally confirmed by the reference slide shown in Fig. 3(a).
Results In health centres using clinical diagnosis, although 413 of 414 patients were negative by the reference slide, 412 (99%) received a malaria drug and 47 (11%) received an antibiotic.
One dose of artemisinin combination therapy was correctly given to the patient with accurately detected falciparum malaria and to three patients with clinic slides that were false positive for falciparum malaria (two were negative and one was positive for vivax malaria by the reference slide).
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Representative pollen grains on the reference slides were photographed at 400× 1000× magnification.
This proportion was defined as patients who were positive for malaria parasites by reference slide and received an appropriate malaria drug and patients who were negative by reference slide and did not receive a malaria drug and were therefore independent of the slide positivity rate.
The brightness of the mercury lamp on different days was normalized by fluorescent reference slides (Fluor-REF, Microscopy Education, Microscopy & Imaging Place Inc., McKinney, TX).
To determine the prognostic significance of the clinical signs and symptoms, a logistic regression model was constructed with the positive malaria slide by the reference laboratory as the dependent variable and the age group and signs and symptoms of severe disease as independent variables.
Areas containing >50% tumour cells were selected by microscopic evaluation on a reference slide stained with H&E.
For reasons of quality assurance, all participating pathologists received a training set of histological slides, provided by the reference pathologist that contains 20 cases of all kinds of breast pathologies.
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by the reference cantilever
by the reference laboratory
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by the reference mapping
by the reference point
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by the reference genome
by the reference structure
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by the reference flow-cell
by the reference phase
by the reference rater
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by the reference transcoder
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