Sentence examples for by the reduced expression from inspiring English sources
We have shown that block of the TRPV1 receptor can be effective in inhibiting trigeminal activation, as seen by the reduced expression of c-fos in the TNC.
Within the 11-day differentiation protocol of the assay, embryonic stem cells lost their pluripotency, evidenced by the reduced expression of stem cell markers Pou5F1 and Nanog.
According to classical notions the differentiation of tumor cells during the breast cancer development is accompanied by the reduced expression of CD-44 receptor with its gradual disappearance and appearance of the cells expressing the CD24 marker [3].
Using mouse primary microglia and RAW264.7 cells, we found that some thiourea derivatives significantly enhanced microglial Aβ phagocytosis and suppressed microglial immune responses, as evidenced by the reduced expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX-2).
However, extending the culturing time to 6 days in each passage caused significant loss in cell viability and induced differentiation as indicated by the reduced expression levels of SSEA-1 and Oct-4.
Moreover, the cold sensitivity of PRLR KO neonates is also amplified by the reduced expression of β3Adr, a key effector for UCP1 expression in rodents [23].
This possibility is greatly strengthened by our finding of the reduced expression of NEUROD1 in CSB knockdown cells and that neurod1 promoter is also bound by CSB.
In addition, some of the miRNAs targeted HNF4α by blocking HNF4α translation, causing the reduced expression of HNF4α protein while leaving transcript levels unchanged (Ramamoorthy et al. 2012).
Unlike that observed for iNOS, acetaminophen did not appear to affect the regulation of nNOS or eNOS expression (Figure 5B) suggesting perhaps that the normalization of Akt S-nitrosylation by acetaminophen may be dependent on the reduced expression of iNOS.
Thus, the reduced expression induced by milatuzumab in vivo may impair cell migration and prevent their proper participation in immune responses.
Using reporter constructs we demonstrated that the transversion leads to increased gene expression to such a degree that the A-allele is able to compensate for the reduced expression mediated by the T-allele of rs143383.
