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Large multicenter acute stroke trials demand a randomization procedure with a high level of treatment allocation randomness, an effective control on overall and within-site imbalances, and a minimized time delay of study treatment caused by the randomization procedure.
To assess whether there was any evidence of systematic imbalance introduced by the randomization procedure, we also undertook formal statistical testing of differences in baseline characteristics between treatment arms using independent samples t tests and Fisher's exact test or chi-squared tests, with significance set at the 5% level.
This structural effect cannot be smoothed by the randomization procedure because it preserves the degree distribution.
Treatment was either neurosurgical clipping or endovascular coiling; we used treatment as allocated by the randomization procedure.
In accordance with the intention-to-treat principle, the primary analysis will compare treatment groups defined by the randomization procedure and will include all events observed during the study irrespective of adherence to assigned treatment.
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Trial quality was assessed by evaluating the randomization procedure, population description, blinding, documentation of cointerventions and whether patient selection was consecutive.
By default, the randomization procedure accounts for differences among chromosomes; for example, the X chromosome contains many sequence features that are atypical of autosomes.
Regardless of the approach used for the determination of tuberculous infection prevalence, there was little difference between the ZAMSTAR study intervention arms produced by the randomization procedures (Table 4).
All statistical inferences controlled for cluster effects at the municipality level and for the stratification (by region) in the randomization procedure.
The pediatrician administers the randomization procedure by assigning the next available envelope as each case is enrolled into the study.
A network is clusterized by biased edge-rewiring similar to the randomization procedure but some rewirings may be suppressed if they result in unfavorable edges which connect nodes from different cohesive groups.
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by the randomization sequence
by the randomization representative
by the averaging procedure
by the learning procedure
by the randomization test
by the bootstrapping procedure
by the randomization list
by the weighting procedure
by the randomization algorithm
by the immortalization procedure
by the randomization programme
by the matching procedure
by the randomization schedule
by the microdilution procedure
by the randomization visit
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