Sentence examples for by the primary sequence from inspiring English sources

This arises because the CPASS similarity is not confined by the primary sequence of the two proteins, but simply captures the spatial orientation of conserved residues around a ligand binding site.

Similar to previous predictors, we have observed that most of the prediction accuracy is provided by the primary sequence and hydrophobicity information.

We here suggest a dedicated novel sequence feature "RNA_editing" that is compatible with the grammar of the GenBank flat file format and might hence be considered for future adaptations by the primary sequence databases (Fig. 2).

Both characteristics are determined by the primary sequence of the protein which very often shows a high number of certain amino acids such as glycine, cysteine, histidine, proline, tyrosine, arginine, lysine and serine.

Oliveberg explained these results by suggesting that all ferredoxin-like proteins comprise two overlapping foldons, but that the specific folding pathway is determined by the primary sequence of each domain [ 18].

These properties will in part be directed by the primary sequence of the SVA to allow for such as interaction with transcription factors and other modulators of genome function acting as sequence specific binding proteins.

(6) In each case, the properties of the assembled peptides are typically defined either by altering the primary sequence and solution conditions to change physical properties, such as strength and type of assembly, or through the addition of ligands or cargo, for instance, the deposition of metal nanowires or other polymers templated by amyloid fibril formation.

As predicted by analysis of the primary sequence and on the basis of backbone dihedral angles and characteristic NOEs, the solution structure shows two well-defined α helices encompassing residues 6 16 and 26 35.

The finding that LRRK2 interacts with 14-3-3 14-3-3 14-3-3d not be predisoforms analysis of the primary sequencouldecause the residues surrounotng the phosphorylation sites at positions 910 and 935 do not adhere to the optimal mode 1 and 2 consensus bending motifs for a common mode of 14-3-3 interaction [ 17, 18].

Regions between helices are single stranded and overlap by one residue in the primary sequence with adjacent helices.

Our biochemical data indicate that the enzyme is constitutively active, and this is supported by bioinformatic analysis of the primary sequence.