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The process of development and the commitment to differentiate is guided by the ordered expression and repression of genes required to enforce specific transcriptional programs.
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The differences between both approaches can also be seen by visualizing the ordered expression matrices (data not shown).
Cell differentiation and self-renewal are paralleled by a timely, ordered expression of a set of cytokines, growth factors and corresponding receptors.
The differentiation of ESCs toward cardiac populations that include cardiomyocytes are characterized by a temporally and spatially ordered expression of specific genes.
Each of these complexes control distinct checkpoints at G1- and S-phase by regulating the ordered of expression of the cyclins that ultimately drive the progression of the cell cycle.
The efficient adhesion and directional movements of tumor cells migrating on the surface of a fibroblast layer can be explained by the ordered structure of ECM facilitated by the expression of syndecan-1 on the surface of fibroblasts [ 51].
In brief, the distribution of the concentrations on any cycle is approximated by the first order expression (15), and this procedure is applied recursively for the vertices that represent glued cycles.
Previously we have shown that spheroid forming capacity in CRLM is reflected by the order of expression of ALDHhigh > CD133 > CD26 [26].
Further, the power law can be applied to describe the data by using the second order expression with respect to ozone and Nap concentration.
Let n be the total number of samples from all classes, r i be the rank of the i th sample determined by the order of its expression value among all samples, N be the number of stages, and p i be the proportion of samples from class i.
The experimental results show that the reaction rate can be quantified by a first-order expression with activation energy E′a of 94.01 kJ·mol−1 and the corresponding pre-exponential factor A′ of 3.39×108 cm3·g−1·s−1 when NH3 is excessive.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com