The first step is represented by the optimization of the operating parameters.
Thermostability of enzymes can be improved by the optimization of unstable residues via protein engineering.
The computational framework is verified by the optimization of three-dimensional wing structures.
RNA comparative modelling was performed using ModeRNA40, followed by the optimization of local geometry and protein-RNA contacts with the Bio+ version of the CHARMM force field using Hyperchem 8.0 (Hypercube).
Second, the application of the algorithm is shown by the optimization of a middle vessel batch distillation.
By the optimization of the gas environment during the reaction, it was possible to obtain high loading of 39.5 wt% with a 2.8 nm size of Pt particle.
Thus, the methodology ensures the detection and the localization of a defect of a component by the optimization of the position of a limited number of sensors.
The detection of extremely low forces, require producing micromachined cantilevers with as small as possible spring constants, which is considered by the optimization of the sensor design.
In addition, an additional energy saving of 1.8% was obtained by the optimization of the operating sequence and refrigerant recovery operation.
Particle separation in hollow-fiber flow field-flow fractionation (HF FlFFF) has been recently improved by the optimization of the HF FlFFF channel design.
The advantages of these applied methods will be proven by the optimization of well-known benchmarks for metallic supported I-beam and gearbox design.
