The disease is caused by the mutation of a single gene that determines the structure of the hemoglobin molecule.
Women are thus carriers of, but rarely suffer from, diseases like haemophilia which are caused by the mutation of X-chromosome genes.
Ponatinib was unaffected by the mutation of the threonine residue and interacts with other residues.
We show that the folding of the proteins was severely disturbed by the mutation of the tryptophan residue.
Constitutive activation of Wnt signaling caused by the mutation of tumor suppressor APC leads to breast cancer stem cell (BCSC) expansion.
Furthermore, we demonstrate that the mutation of either T242 P or U7-U8 compensatesathetheffectcausedsed by the mutation of R7A on the replication of rVSVR7A.
Therefore, species specificity of the genetic control of floral development may result in differences in the phenotypes caused by the mutation of orthologous gene, such as rice Ehd2/RID1/OsID1 and maize ID1.
Phenotypic differences caused by the mutation of allelic genes also exist between subspecies or varieties of rice (Matsubara et al. 2008; Park et al. 2008; Wu et al. 2008).
Most common pathologies in humans are not caused by the mutation of a single gene, rather they are complex diseases that arise due to the dynamic interaction of many genes and environmental factors.
Both the sterile lemma elongation and the floral organ number increase phenotype are enhanced by the mutation of an independent gene SMALL DEGENERATIVE PALEA1 (SDP1), whose single mutation causes reduced palea size.
Studies of the genetic sequences that encode these proteins, and of phenotypes caused by the mutation of these sequences, have been used to characterize the membrane transport of plant secondary metabolites.
