Sentence examples for by the molecular function from inspiring English sources
Given a motif of some source protein, associated with its target protein, the combined filter examines whether the source and target proteins are retained by the molecular function filter, as well as whether the motif and source are retained by the frequency score filter.
Their occurrence is slightly favoured by the sequence context but mainly determined by the molecular function of the gene.
Selected genes within the extracellular space ontology were then organized into subcategories that were significantly represented by the molecular function ontologies (P < 0.01).
In total, the highest number of SNPs/gene was in the cellular component category (11.96), followed by the molecular function (8.02) and biological process (7.92) categories (Table 4).> -wrap-foot> 1)HAU-SNP001 ~ 356.
Further analysis of the list of TNFα-regulated, MEK/ERK-dependent genes – whose products are found in the extracellular space – indicated that some of these genes were significantly categorized by the molecular function of their protein products into categories that included hyaluronic acid binding activity (including Agc1 and Hapln1) and proteinase activity (including Mmp-9 and Mmp-12).
The differential regulation of DNAJC12 may also reflect general transcriptional changes by maintaining the molecular function of estrogen receptors together with HSP70 [ 77].
Gene Ontology (GO) analysis was performed using DAVID (http://david.abcc.ncifcrf.gov) [ 48], by examining the molecular function in which genes hosting miRNA(s) are involved, using Ensembl Gene IDs and the entire human genome as a background model.
Future experimental work will hopefully shed more light on this issue, notably by investigating the molecular function of Sxl splice forms that are produced equally in both sexes and so may perform one the of the ancestral function of the gene.
By randomly shuffling the molecular function annotations we showed that cross-validation AUC values equal to or greater than 0.7 are unlikely to be obtained by chance (P<0.01).
The enrichment in this biological process was reflected by enrichment in the molecular function GO term "chlorophyll binding" and the cellular component GO term "photosystem I" and "photosystem II" in PVYO-inoculated Premier Russet (see Additional file 4).
Besides technical factors, the disparity may result from the fact that diseases are directly caused by the perturbations of the molecular function that are generally carried out by a set of genes in the form of modules or pathways.
