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The heterogeneity can be explained by the methodological diversity of the reviewed studies, including the design, study site, study period, cluster definition and fingerprinting techniques applied, which may have different discriminatory power [ 37].
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The study of the quality of life reflects the methodological diversity of scientific inquiry, the quantitative approach being the one most often used (see Table 1).
These differences might be derived from the varied severity of psychiatric disorders among the samples in addition to the methodological diversity of PD assessment.
Surely, synthesising the data descriptively will not make the problem disappear – the same uncertainty regarding bias introduced by methodological diversity in the measurement of PA persists.
We will not attempt meta-analysis if considerable heterogeneity (I>75%) cannot be explained by the clinical and methodological diversity.
The clinical and methodological diversity among the studies was assessed to determine the appropriateness of data pooling for meta-analysis.
Finally, a meta-analysis was not performed because of concerns that the clinical and methodological diversity (heterogeneity) of the included studies would make the process meaningless.
In general there is considerable heterogeneity between the studies and between subgroups; methodological diversity between studies may explain the heterogeneity.
16 Study heterogeneity (clinical and methodological diversity) among the trials was evaluated by abstracting data on study design, included populations, and definitions of outcomes.
(7) This meta-analysis was notably plagued with heterogeneity (i.e., large clinical and methodological diversity among the various studies reviewed) and included studies designed with inherent biases and potential confounders (observational and cross-sectional studies).
We were unable to perform a meta-analysis due to methodological diversity of the included studies.
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