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We think that the differences might be caused by the methodological differences; different self-reporting questionnaires may reflect different findings.
The difference in migraine prevalence between our study and other studies could be explained also by the methodological differences or different self-reporting questionnaires used and the time of the study which differs with various studies.
Some of this large difference could be explained by the methodological differences used by the different studies.
The inconsistencies across studies may be explained by the methodological differences used in the determination of PTEN and PIK3CA.
However, our findings and the findings of Fujii et al. found no clear relationship between DPD activity and 5-FU sensitivity.[ 8] This discrepancy could be explained either by the methodological differences or the broad range in systemic DPD activity.
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This resource will greatly facilitate population genomic analysis in this model species by reducing the methodological differences between data sets.
As expected and also noted with the physician-coded CoD in a large-scale national survey BDHS 2011 (2), the rank-order of the InterVA-4-coded CoD changed markedly by age group despite the methodological differences (in terms of questionnaires used, length of the recall period, assessment and categorisation of CoD, and time period).
This alternative, yet complementary, prediction capability is a consequence of the methodological differences exhibited by the approaches investigated here.
An alternative explanation is the methodological differences between studies, caused by a wide range of risk accuracy measures [ 38].
With respect to the study by Dudley et al. [27], the methodological difference is that here the authors used a partial SDE composed only of genes with significant differential expression in skeletal muscle atrophy, rather than using a genome-wide SDE.
The variation observed between identified hotspots by the nucleases might be explained by the intrinsic methodological differences between TACh and the DNase I-based assays.
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