Sentence examples for by the maximum dose from inspiring English sources

For translational purposes, the number of combined VHH probes may be limited by the maximum dose possible to administer for imaging purposes, and the clinical testing may be prolonged by the need for single-probe testing prior to the cocktail testing in patients.

We calculated the percentage maximum dose by dividing the maximum dose in each study by the maximum dose allowed for the study drugs.

During a period of 16-week treatment, only two patients who could not achieve the BP goal by the maximum dose of amlodipine (10 mg/day) were additionally administered valsartan 80 mg/day and hydrochlorothiazide 12.5 mg/day, respectively.

Lyophilized ODTs are also limited by the maximum dose that can be delivered, usually < 400 mg for poorly water-soluble drugs and down to ∼ 60 mg for water-soluble drugs [66].

Standards for noncarcinogenic chemicals, for instance, are defined by the maximum dose that causes no harm to animals in a toxicity study, divided by numerical factors to reflect data uncertainties.

The results of SNP analysis of genes associated with tacrolimus pharmacokinetics indicated that CYP3A5 *3*3 was significantly more frequently observed in patients of the low dose group than in those of the high dose group (19 (90%) vs 5 (31%), p = 0.001).> -wrap-foot> aPatients were divided into two groups by the maximum dose (<0.2 mg/kg or ≥ 0.2 mg/kg).

Since 6 animals in the 2% male group died of hemorrhage of several organs by week 50, the maximum dose level was changed to 1% in both sexes for the last 2 weeks.

The maximum dose to the spinal cord increased in all patients by 0.2 15.4 Gy, and the maximum dose to brainstem increased by 0.6 8.1 Gy in 85% of patients in hybrid IMRT plans.

This is slightly more than the dosage recommended by EMEA, but less than the maximum dose recommended by the manufacturer (4 tablets) and far below the maximum recommended daily dose of nine grams.

The vasoconstriction induced by phenylephrine in rat mesentery was antagonized by prazosin with a significant reduction of the response to the maximum dose and by phentolamine with a significant reduction of the response to the maximum dose from 110 ± 36 to 13 ± 4 mmHg (P < 0.001).

74 It is suggested to start metformin from lower doses and reduce the maximum dose by about 50% in patients with eGFR<60 mL/min, rather than strictly avoid the drug, even in oldest-old adults.