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Although the study design allows no statistical analysis, these conclusions are supported by the marked differences in K+ levels in gray and white matter induced by the different toxicants.
(3) The comparability of results between studies is severely limited by the marked differences in the methodologies and definitions applied.
This is illustrated by the marked differences in cardiac contractility, electrophysiology, and energy metabolism in the absence of TH (hypothyroidism) and presence of excess levels (hyperthyroidism) [ 4].
Our approach, which used exercise-test outcome as a proxy for coronary disease, is supported by the marked differences in the cardiovascular event rates experienced by our patients.
The strong influence of proliferation was further highlighted by the marked differences in CIN70 metagene expression between classification groups for the DCC classifier across investigated data sets (in Additional file 5: Figure S2).
Genetic factors are likely to play a major role here, as implied by the marked differences in the incidence rates between Hong Kong Chinese and Chinese Americans, the former being mainly Cantonese originating from Guangdong Province, whereas the latter have more diverse origins.
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Thus these two models didn't appear relevant for such high level of pure drift divergence as expected by the marked difference (even for SNPs with ancestral reference allele frequency close to 0.5) between the expected distribution of within population allele frequency [24] and the distributions assumed in the models (Figure S3).
As shown above, YjgB strongly prefers unbranched substrates, which is well demonstrated by the marked difference between n-butyraldehyde and isobutyraldehyde.
The difference in specificity between the two studies is reasonable because critically ill patients generally maintained higher 'normal' CRP levels than did the ED patients, which is immediately evident by the marked difference in median CRP levels (56 mg/l versus 5.3 mg/l) between noninfected patients of the two studies.
When comparing the total number of CNV events between the two groups Nexus suggested a trend towards significantly more events for the MMR negative group (p = 0.0509), but the converse was observed in QuantiSNP (p = 0.0021) and to a much lesser degree; likely reflected by the marked difference in event frequencies called by the two methods.
This assumption was supported by the marked difference in influenza activity in the province of BC between the two periods of April to August and September to December, based on both laboratory-confirmed cases and physicians' visit counts (see Figure S8, Additional file 1).
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