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Therefore, the potential benefit of preventing activation of Map17 is partly negated by the lower expression level of the transgenes.
Therefore, the enhanced dopaminergic transmission produced by the lower expression level of Dysbindin may be partially attributable to activation of MARCKS.
Therefore, the benefits of partially preventing insertional gene activation are in part negated by the lower expression level of the transgene.
The metabolism of glucose and carbohydrates seems also to be hampered by early protein restriction as indicated by the lower expression levels of several genes involved in this metabolic pathway including lactate dehydrogenase C, UDP-glucose pyrophosphorylase, mannosidase alpha class 2A, malate dehydrogenase 2 and xylosyltransferase1.
The attenuation of H37Ra involves a failure to adapt to both changes in the environment and metabolic constraints, evidenced by the lower expression of genes involved in mycobactin synthesis and fatty acid metabolism when the attenuated strain is moved from broth culture to the macrophage.
These strains were highly attenuated in growth rate, which is likely caused by the lower expression of the PPC enzyme.
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Thus, in sample FS-11, 7 out of 11 pathways of amino acid metabolism were highly deactivated by meaning of the lower expression level (2.6- to 117-fold) of proteins assigned to those pathways, compared with FS-0.
A possible explanation of smaller increases in satiety hormones by fructose could be the lower expression of GLUT5 in β-cells [ 60] or lower absorption rates in the intestine [ 61].
The induction of leaf necrosis by DIII may contribute to the lower expression level as it may shorten the window for accumulation.
Note the lower expression of CD44, by comparison, in the ES and EC cells.
The leading cause of reduced mitochondrial activity appears to be the STAT3-mediated down-regulation of nuclear genes encoding for mitochondrial proteins, mirrored by the lowered expression of ETC components.
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