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The fructose component of sugar and H.F.C.S. is metabolized primarily by the liver, while the glucose from sugar and starches is metabolized by every cell in the body.
Attributing to the PEGs covering and cyclic RGD conjugation, cRGD-GNPs targeted tumor more efficiently and avoided heavy capture by the liver, while part of the nanoparticles were still absorbed by the gallbladder.
The majority of LDL-C (≈ 75%) is taken up by the liver, while the remainder is removed by peripheral tissue.
Voriconazole is mainly eliminated by the liver, while kidney elimination is negligible, and less than 5% of the active drug is found in urine.
SAA and PON1 are chiefly produced by the liver, while localized synthesis of SAA has been shown in atherosclerotic lesions, which are accompanied by inflammation and oxidative stress [ 18].
Primary bile salts are those synthesized by the liver, while secondary bile salts result from extra-hepatic modifications of bile salts, typically by host bacteria in the colon and distal small intestine [ 1, 8].
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Thus, the lower glutamine concentrations in these septic patients were due to increased clearance by the liver and/or other cells, while intestinal uptake was decreased.
Most up-regulated processes were related to metabolic functions performed by the liver, including lipid and carbohydrate metabolism, while most down-regulated processes related to cell replication and the cytoskeleton.
They further showed that discoidal particles can maximize accumulation in target organs while reducing sequestration by the liver.
ApoB48 was synthesized exclusively by the small intestine, while apoB100 was synthesized by the liver.
While the plasma vitronectin is produced mainly by the liver, the origin of the tissue vitronectin is less clear [8].
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