A linkage map was constructed by using the linkage mapping function implemented in the QTL IciMapping software (Meng et al. 2015).
Hierarchical cluster analysis with mean linkage function (hclust function in base R) was used to cluster the samples by expression profiles.
To obtain the dendrogram, unsupervised hierarchical clustering by sample was performed on all probe sets using BRB-ArrayTools developed by Dr. Richard Simon and BRB-ArrayTools Development Team with centered correlation as distance metric and average linkage as linkage function.
The binding-site sealing, promoted by the linkage of 4bc, prominently inhibit protein mobility, causing a significant reduction of its major mobility-dependent functions.
The jurisdictional linkage keys supplied by the linkage units in NSW and WA were purposely not used during the linkage process, but were used solely to measure linkage quality once the CDL had completed its linkages.
Advances in diagnosis and treatment of some bone disorders can be made by understanding the linkage between mineral content and mechanical function.
Using Euclidean distance as a distance metric, clustering of profiles was performed using the 'complete linkage' clustering algorithm performed by the R function hclust from the stats R package [ 50].
A linkage map was constructed with 282 markers by the Kosambi function, and the QTL was detected by composite interval mapping.
Baker [13] investigated the impact of observational errors on the dendrograms produced by the complete linkage and single linkage hierarchical grouping techniques.
In this microarray analysis, a hierarchical clustering was performed to further examine the relationship among the clinical strains by using a standard correlation function where the linkage distance between strains is represented by branch lengths in the resulting cluster.
