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As metformin is largely excreted by the kidneys, the risk of metformin accumulation is greater in patients with renal impairment.
Because 85% of administered digoxin is excreted by the kidneys, the risk of toxicity from this drug is very high in people with CKD [ 74].
Because BPA is cleared by the kidneys, the pharmacokinetics of environmental phenols could be very different in populations with impaired renal function.
While Sm and Sr are excreted primarily by the kidneys, the major route of excretion of Ra is through the feces, with only a small fraction of renal excretion; this reduces the chances of contamination.
As they are cleared by the kidneys, the main potential limitation of LMWH is the potential risk of bioaccumulation and bleeding when administered to patients with renal failure (Nagge et al 2002).
Using the current model, which does account for blood volume regulation by the kidneys, the hypothesis of Pettersen et al. may be further analyzed by determining how simulations of the current model respond to changes in the aortic compliance.
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The amount of DNA was found to be highest in the liver followed by the kidney, the blood, and least found in the gills, i.e., liver > kidney > blood > gill.
In drugs that are mainly excreted by the kidney the rate of elimination is also generally reduced in the elderly.
Recovery of GSH content was fastest for the liver followed in descending order by the kidney, the lung, the bone marrow, RBCs and the heart.
Produced by the kidneys, EPO regulates the production of red blood cells.
Erythropoietin, known as EPO, is produced naturally by the kidneys and stimulates the production of red blood cells.
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