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However, the effectiveness of these procedures is strongly affected by the initial model uncertainty, leading to suboptimal design solutions and higher number of experiments to be executed.
At first, samples with strong discriminant cues will be correctly classified by the initial model and obtain stable posterior probabilities.
On the third column from the left, the mean residual refers to the average difference between a given measurement and its prediction by the initial model centered at epoch t c =2014.3 (see text for details).
Therefore, a candidate architecture (a location in such n-dimensional space) is formed by the initial model extended with the merge of all architectural extensions provided by all involved variation points.
As expected, the following two features are not explained by the initial model: (1) the real arrows to the east of the volcanic front are pointing towards each other at 16 s and (2) the large northward arrows at northeastern sites at 64 and 256 s.
This biphasic behavior was not accommodated by the initial model of HBV viral dynamics developed by Nowak et al. [37].
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These bars were calculated by modifying the initial model in 5% for the every density contrast.
The different models were calculated by varying the initial model and optimizing the objective function using conjugate gradients and molecular dynamics with simulated annealing using the CHARMm force field.
The responses observed are compared with those predicted by the initial models, which are refined to account better for the results.
The added value provided by the initial models to such research activities largely depends on the quality of those models.
Nine variables relating to supportive nursing care across the disease journey were introduced to the final analysis to assess whether men's experience of nursing care could explain any variation over and above that explained by the initial models.
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