Sentence examples for by the initial lymphatics from inspiring English sources

Due to its association with albumin, we have found that ICG is preferentially and rapidly taken up by the initial lymphatics when administered intradermally.

ICG is rapidly taken up by the initial lymphatics and upon surface illumination with tissue-penetrating NIR excitation light, the fluorescence generated by the ICG-laden lymph is collected with high temporal resolution to visualize transport and lymphatic "pumping" activity.

NIRF imaging depends upon the intradermal administration of the fluorescent dye indocyanine green (ICG), which is actively taken up by the initial lymphatics in the dermis and transits to collecting lymphatics through a series of lymphangions, or segments of "pumping" vessels, that conduct lymph to draining lymph node basins.

Intravital fluorescence imaging was also conducted after a midline incision of the abdominal skin from the inguinal to the axillary regions to confirm that ICG was picked up by the initial lymphatics and drained to LNs through the contractile, collecting lymphatic vessels.

As demonstrated in Fig. 3, non-invasive whole-body fluorescence imaging data correlated with intravital fluorescence and EBD images, demonstrating that both ICG and EBD were taken up by the initial lymphatics and drained from the ILN, through the contractile collecting lymphatic vessels, to the ALN.

ICG was not associated with any apparent vessel, suggestive of lack of uptake by the initial lymphatic capillaries and extravascular transport.

Similar to ICG, EBD also binds to tissue macromolecules and is selectively taken up by the initial lymphatic vessels [ 21]. Figure 3C shows the lymphatic drainage of EBD along the lymphatic vessels, which is the same lymphatic flow pathway depicted by ICG fluorescence in Fig. 3B.

These vesicles are drained rapidly from the injection site into the initial lymphatics when compared to unmodified liposomes, and are retained more favourably by the scavengers of the regional lymph node.

Microfilariae were often close to the initial lymphatics but their presence inside them was not observed (Figure 4D).

There is no macromolecular size-dependence in the filling of the initial lymphatics (unlike macromolecular permeability through blood capillaries) [62], thus protein concentrations drained through the lymphatics were modeled as continuous with those in the available interstitial fluid.

Initial lymphatics have been excluded from these analyses on the basis of morphology (note the increased calibre of the initial lymphatics) and differential staining for Lyve-1, podoplanin and collagen IV (Supplementary Fig S1).