Based on a previous principal component analysis, psychosis (delusions, hallucination), agitation (agitation/aggression, disinhibition, irritability) and affective (depression, anxiety) sub-syndrome scores were formed by summing the score of the included items [ 50- 53].
For comfort, a sum score for comfort was calculated for the included items and divided by the number of items included in the score in order to obtain a mean value.
The centrepiece of the display was a scale model of Centaur presented to the Memorial by Blue Funnel Line, and the display included items that were donated by the survivors, such as a lifejacket, a signal flare, and a medical kit.
Tooth eruption phenotypes of the children were derived from questionnaires completed by the mothers and included items regarding the 'age at first tooth' (assessed at 15months) and the 'number of teeth' in the child's mouth (at 15 months).
Direct costs represented services that were used by the patient and included items such as the costs of physicians employed directly by the hospital, treatment costs, and food [ 19].
The assessment instrument used by Opper (1996) included items in the following five domains: motor development, personal and social development, cognitive development, language development, and development of pre-academic skills (Opper 1996, p.11).
Content validity was assured in the construction of the questionnaire by including items derived from the qualitative interviews and the literature and by having the appropriateness of included items reviewed by a multidisciplinary team.
While patients discussed a number of emotional impacts that are not specifically addressed by the LPH, including items to assess all of the emotional impacts would add significant respondent burden.
HPA axis function was evaluated by the TSST, which includes items assessing the essential features of a reliable stressor being both uncontrollable and social-evaluative [ 20, 21].
However, the initial stages of development and preliminary testing will be undertaken by the researchers including item generation and selection, establishing content validity, and testing comprehensibility to patients.
