Sentence examples for by the genetic complexity from inspiring English sources

More effective therapies are also crucial in PDAC, since progress in identifying novel therapies has been hampered by the genetic complexity of the disease and treatment remains a major challenge.

This can be explained by the genetic complexity of the disorders and the small sample sizes of certain studies.

The ongoing research to detect genes or pathways frequently altered in OS and the search for new therapeutic and prognostic procedures is hampered by the genetic complexity of OS.

Although genetic studies promise to improve our understanding of the pathophysiological and genetic aspects of the depressive syndrome, such understanding is limited by the genetic complexity and lack of discrete, etio-pathologically related, and homogeneous "depression" phenotypes.

Commodity soybean oil typically contains 20% oleic acid and the target for high oleic acid soybean oil is approximately 80% of the oil; previous conventional plant breeding research to raise the oleic acid level to just 50-60% of the oil was hindered by the genetic complexity and environmental instability of the trait.

Over the last years, single-cell genomics (SCGs) has enabled sequencing of individual genomes of many abundant and ecologically important prokaryotes in marine and other environments12,13,14,15,16 by disentangling the genetic complexity of the community to the minimum level, the cell.

Recent molecular work sheds light on the genetic complexity discovered by Lewis and demonstrates that Ubx executes its developmental role by producing a family of closely related DNA-binding proteins that can function as transcription factors.

These studies were followed by genome-wide association studies elucidating the genetic complexity of CD with HLA class II alleles as major contributing factors [ 9].

Array-based genomic profiling of ESCC confirms the genetic complexity suggested by earlier studies that have applied other means of genetic profiing, e.g. cytogenetics, conventional CGH, and LOH analysis.

5 We, therefore, applied a new approach to unravel the genetic complexity of FS by employing a phenotype-driven genetic strategy in a controlled laboratory setting inducing experimental complex FS by hyperthermia in mice.

A part of the genetic complexity could be caused by reciprocal, differential regulation of the hormone biosynthetic genes by various hormone-signaling pathways, as it has been shown that in seedlings BR and GA antagonistically regulate the accumulation of mRNAs of the GA-regulated GASA1 and GA5 genes [35].