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The results show that the predictions by the general model are closer to the actual experimental results.
Averaged core analysis data from wells located in this area (Børglum-1 and Flyvbjerg-1; Fig. 1) point to permeabilities higher than indicated by the general model.
For this, the expected fitness values under the assumption of no epistasis were calculated from the experimentally determined fitness values and used to analyze the respective steady state frequencies assuming a mutation-selection equilibrium as defined by the general model of HIV quasispecies dynamics [44].
For even larger phylogenomic data one can use PROCOV to analyse several competing trees that were already established by other phylogenetic methods and see which of them is preferred by the general model.
Despite very different assumptions about the effects of mutations on specific activity, the four cases yield the same qualitative result: evolutionary rate decreases with expression level, as predicted by the general model.
Although the resulting values for τ from the classical model deviate noticeably from the general model for most cases, they agree within the probable physiological ranges of [GPxr] and [H2O2] suggested by the general model.
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By applying the general model described by Eq. (7) to all the major types of vertebrates (including endotherms: primates, dolphins, mammals and birds, and ectotherms: fishes, reptiles and amphibians), we found that the actual brain masses and model predictions were aligned well in a log-log plot.
We can see this by using the general model f(x) = n · x m.
We start by describing the general model approach and explaining the methods used to estimate fishing-induced selection differentials.
As before, the test is carried out by fitting the general model as well as the restricted model under the null hypothesis and calculating the likelihood ratio statistic.
The set of model-based tools that can be applied in each design stage is expanded by automated model transformations via the general model exchange format CIF (http://se.wtb.tue.nl/sewiki/cif).nl/sewiki/cif
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