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The active site is a groove or pocket formed by the folding pattern of the protein.
This mechanism is thought to involve physical contact between these regulatory elements and their target promoters, which is permitted by the folding pattern of the chromatin fiber.
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The inconsistency of the in vitro and in vivo results could be explained by slight differences in the folding pattern of the intein, which would again indicate sensitivity in the described network to minor disruptions in bonding or folding patterns.
In two cases, COI and COIII, intramolecular interactions between spatially linked residues restore the folding pattern impaired by the deleterious mutation.
Limitations in the software (maximum sequence length is 450 bp) only permitted the analysis of partial ITS2 sequences and these were derived from nucleotide 240 to the 3' end based on the folding pattern obtained by MFOLD.
The folding pattern of the polypeptide chain has been elucidated by X-ray crystallography.
The amount of light recorded by the camera therefore tracks the distance between the fluorophore and the heme and thus the folding pattern of the protein.Of course, things are more complicated in practice.
To maintain the folding pattern of the single-molecular tetrahelix (Fig. 1b) and to make the interaction specific, we introduced shape complementarity, i.e., an interlocking mechanism, by nicking (G3T 3 within the middle (2nd) G3T unit (Fig. 1).
However, the variability of the folding pattern across individuals creates a lot of difficulties.
The folding pattern revealed also a cationic site and spatially adjacent hydrophobic stretch.
Secondly the folding pattern of the membrane, which takes advantage of the symmetrical deployment offered by the petal hub, is developed and the unfolding mechanism is verified by numerical and experimental analysis.
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