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The increased gene and protein expression levels of PI3K in liver were observed in the extract groups, while the expressions of JNK1 were significantly downregulated by the extract.
Bilateral carotid artery occlusion (BCO) caused a reflex increase in mean arterial pressure and heart rate which were significantly attenuated by the extract injection.
It may also be due to direct activation of GABA receptor by the extract [38].
These ultrastructural changes confirmed that cell damage was caused by the extract.
Histopathological changes induced by high cholesterol diet were also significantly reduced by the extract.
Figure 5a‒c show the Ag-NPs surrounded by the extract of GSH.
However, the percentage inhibition of the DPPH radical by the extract was lower than that of ascorbic acid.
In FACS assays, 3.8% of CD4+ cells produced IFN-γ when stimulated by the extract.
We compared the spectrum of the product produced by the extract with the spectra of metallic tellurium and potassium tellurite reduced chemically with 2-mercaptoethanol, as standards.
However, many LPS-responsive genes with or without NF-κB binding sites were not induced by Astragalus and suggests alternate modes of gene regulation by the extract.
