Sentence examples for by the conditional mutations from inspiring English sources

Finally, we provide evidence that periV neurons, the only other group of neurons targeted by the conditional mutations, are not involved in the chemoreflex.

In the following sections, we describe the conditional mutations we have characterized for each affected locus.

Using cre/loxP recombining system driven by the cytokeratin (K 14 promoter to induce the conditional mutation of β-catenin in mice, Peter Wend's Laboratory demonstrates that the epidermis of young mutant animals develops normally but without hair [ 10].

All of the mutants died during embryonic development, indicating that the conditional mutation is embryonically lethal.

It indicates that the conditional mutation might be a factor in shaping the codon bias but not the unique one.

The presence of calcium resistant (CaR), hs+ progeny would have signified a lack of cosegregation between the scr mutation and the conditional mutation (Table S2).

Although these features are recapitulated in a mouse model of soft tissue sarcoma initiated by conditional mutations in Kras and Trp53 [5], it is not clear whether this model is most similar to human MFH or another soft tissue sarcoma.

In the first article, Han et al. (2005) described a mutation in the pantothenyl transferase, ngA1, that resulted in a lack of pigmentation in the conidia and the hyphae that could be suppressed by a conditional mutation in a second gene, snpA6, at 37° and 42°, but not at 25°.

Generation and validation of the Ptbp2 conditional mutation.

Their large‐scale implementation by several international mouse mutagenesis programs will lead to the assembly of a library of ES cell lines harboring conditional mutations in every single gene of the mouse genome.

Here we describe 24 conditional mutations that affect 13 different loci and report the identity of the gene mutations responsible for the conditional lethality in 22 of the mutants.