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The fundamental role of the PI3K pathway in ESCs, as suggested by the computational analysis, is supported by different lines of experimental evidence.
Therefore future work for S. stipitis can be focused on the experimental testing of strain design hypothesis generated by the computational analysis.
Our own strategy is focused on testing the drugs and treatments proposed by the computational analysis of genomic information in animal models as a key clinical element.
Helitrons, a new category of DNA TEs, have recently been uncovered by the computational analysis of genomic sequences of A. thaliana, O. sativa and C. elegans [ 3].
Multiple bands are not common in the Phi class, probably thanks to more reliable gene structures inferred by the computational analysis and, as a consequence, to a more specific primer design.
In general, the networks derived by the computational analysis of these data are static, in the sense that they provide little information, if any, about the flow of causality and events in the process and no information about the dynamics of the processes and its regulation (however, see [ 11]).
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Cases of failed statistical clustering can be addressed by refining the computational analysis method.
By initiating the computational analysis with one LexA binding sequence and querying the whole promoter set of Escherichia coli K12 (motif length 20, same parameters as for AtoC), we identified a number of putative DNA binding sites, including thirteen known LexA binding sites.
By applying the computational analysis on human microarray data, we uncovered a unique expression pattern of TACSTD2 in breast cancer, and experiments confirmed TACSTD2 show bimodal behavior in breast cancer cell lines, further, our perturbation study suggest a potential bistable mechanism is involved.
The experimental design was conceived by JW, TK, MH, and NHC and all experiments were performed by JW except the computational analysis.
Moreover, the computational analysis required by these assays is often complicated and it retains a certain degree of discretion.
More suggestions(18)
by the theoretical analysis
by the computational analyses
by the computational burden
by the computational process
by the computational grid
by the computational chemistry
by the computational time
by the computational effort
by the computational domain
by the computational optimality
by the computational complexity
by the computational simulation
by the computational power
by the computational support
by the computational fluid
by the computational cost
by the computational calculation
by the new analysis
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com