Sentence examples for by the common mutations from inspiring English sources

Gatifloxacin has a higher affinity to GyrA and is less inhibited by the common mutations in the GyrA gene [20].

Not all FOP cases are caused by the common mutation, as there are several FOP variants with varying phenotypes.

We have attempted to extend the in vitro experiments by characterizing the molecular pathogenesis of the common mutations, delta F508 and G551D, in the context of a more relevant setting, the pseudostratified epithelium of a proximal human airway.

However, until recently there was a limited understanding of the role of these microRNAs in the skin cancers caused by the most common mutations.

New drugs capable of restoring the CFTR protein damaged by the most common mutations are required.

The first step in MUTYH molecular screening in Caucasian patients is usually represented by the search for the two common mutations.

The strategy of γ-secretase inhibition to slow disease progression is further supported by the finding that the most common mutations that cause familial autosomal dominant AD involve presenilin, a γ-secretase component [ 3].

Therefore, the total number of non-synonymous point mutations detected, comprised 21 reported by both companies, plus 2 additional mutations reported only by WG. 14 of the 21 common mutations including the ones located in regulatory genes (see below), were confirmed by Sanger resequencing (Table 1A).

This virus might be particularly susceptible to co-receptor switching as it has been shown that it has a single pathway to X4 usage that is determined by two common mutations in the V3 loop (I309R and A316V) regardless of whether the selection pressure was exerted by culturing in the presence of CCL5 or by switching cellular substrates [42].

We use two measures between a pair of cells that are expected to correlate well with the length of the common developmental history of a pair of cells: the depth of the MRCA of the pair (as assigned by the reconstruction algorithm), and the percent of common mutations shared by the pair.

and NM_004562 for the cDNA (c).. LRRK2 was screened by sequence analysis for the most common mutations occurring in exons 31 and 41 as previously described [9].