Sentence examples for by the combinatorial control from inspiring English sources

With the constellation of TFs bound, the expression level of a target gene is usually determined by the combinatorial control of a number of TFs.

Gene regulation at the level of transcriptional control involves a complex network of regulatory interactions, one aspect of which is clearly demonstrated by the combinatorial control of individual genes by multiple TFs.

Taken together, these data indicate that YHB1 is regulated by many environmental signals, highlighting the combinatorial control of this gene.

Figure 6 clearly suggests the combinatorial control of gene expressions mediated by TFs and miRNAs simultaneously.

The combinatorial control of gene expression cannot be fully appreciated without considering the co-regulators.

We applied it to analyze the combinatorial control of the key transcription factors in mouse ESCs.

Cis-regulatory modules are central to the combinatorial control of gene expression.

Many examples of the combinatorial control are well known particularly those involved in ABA responses [ 26, 77, 85, 86].

The importance of transcription factors in the regulation of gene expression and their associated mechanisms has been known since the 1980s [ 5– 7] and can be illustrated by the presence of a massive number of transcription factor families and the extensive combinatorial control of gene expression by multiple transcription factors.

This may be due to the binding of multiple additional pluripotency transcription factors at these targets, such that loss of Nanog is insufficient to critically diminish the efficiency of combinatorial control of transcription exerted by the remaining factors.

Recently, transcriptional and post-transcriptional levels of gene regulation have been combined into the hypothesis that combinatorial control by transcription factors and miRNAs may be involved in regulation of the majority of cellular pathways [5,6].