Sentence examples for by the coding polymorphism from inspiring English sources

In contrast, the POase substrate-specific assay reflects both quantity and catalytic efficiency of the PON1 enzyme and is affected primarily by the coding polymorphism PON1 192.

The coding polymorphism, PON1 192, was genotyped using the TaqMan real-time polymerase chain reaction (PCR) method.

Initial studies by our group indicated multiple polymorphisms in these other regions, many of which were not in significant linkage disequilibrium with the coding polymorphisms [9] [11].

The coding polymorphisms of the gene affect the secondary structure of UCN3 mRNA remarkably.

Both groups had similar distribution of alleles and genotypes created by the three coding polymorphisms of LEPR gene.

One of the two exonic polymorphisms is silent (#5), and the other is the Cys/Ser coding polymorphism.

The G2677T polymorphism is a coding polymorphism resulting in substitution of alanine by serine in the Pgp amino acid sequence.

The analysis did not reveal any linkage of these SNPs with the known coding polymorphisms.

For significantly associated mutations, the MatInspector web server [14] was used to screen potential transcriptional regulatory binding site changes caused by promoter polymorphisms, while the Mfold web server [15] was used to predict mRNA secondary structure changes caused by coding polymorphisms.

Specifically, we investigated how the expression and enzymatic activity of antioxidant systems are modulated by a heterozygous missense LMNA mutation, by a non-synonymous coding polymorphisms, and by a homozygotic null mutation in the WRN gene.

We have analyzed human coding polymorphism and interspecies evolutionary changes in the PRDM9 gene.