The relevant genes and clusters were supported by the co-expression network structure, functional enrichment of co-expressed genes, gene expression specificity and literature information.
Indeed, TRPA1 evoked a current in CHO cells expressing TRPA1, and this current was inhibited by the co-expression of TRPV1 (Patil et al., 2010).
Strikingly, although E75 binding was unaffected by the co-expression of UNF, UNF binding was approximately 3- to 4-fold reduced when co-expressed with E75.
This hypothesis is reinforced by the co-expression of TgR AChE with the early immediate protein c-fos, which is expressed in neurons whose activity is strongly stimulated by synaptic input (Dragunow and Faull 1989; Frankland et al. 2004).
However, the protein levels of H3K9ac and H3K14ac were not rescued by the co-expression of TIP60 and UHRF2 in cancer cells (Fig. 5D F).
Similar results were achieved by the co-expression of vascular endothelial growth factor and angiopoietin-1 in the infarct border zone [21].
The conversion of endogenously synthesized l-phenylalanine to styrene was achieved by the co-expression of phenylalanine ammonia lyase and trans-cinnamate decarboxylase.
Characterization of fragment reconstitution was facilitated by the co-expression of two FN3 fragments, thus establishing a yeast surface two-hybrid method.
Improved CAR T cell homing (>10-fold) to CCL2-secreting neuroblastoma and enhanced antitumor activity in vivo were found by the co-expression of CCR2b on GD2 CAR T cells (Craddock et al., 2010).
In eukaryotes, many cellular processes require the coherent participation of multiple gene products as evident by the co-expression of large sets of genes in response to specific stimuli [10, 27, 29].
Moreover, the adjuvant properties of LL-Mig::IP-10 strain were evaluated in mice by the co-expression of a model antigen, the human papillomavirus type 16 E7 protein.
