Sentence examples for by the classical pathway from inspiring English sources
The most studied dimer is p50 p65, which is activated by the classical pathway and usually promotes gene expression.
Consistent with a reduction in complement activation by the classical pathway, the HT transgenic PAC showed a 2-fold reduction in the deposition of complement components C4 and C3 relative to controls.
C4b deposition by the classical pathway was inhibited by the intestinal contents from the three triatomines.
Saliva or soluble intestinal contents, obtained from triatomines were unable to inhibit C1q deposition by the classical pathway.
The effect of IL-10 is mainly on the activation of NF-κB by the classical pathway, since IL-10 inhibited the nuclear translocation of LPS-induced p65 but not of CD40-induced p52.
According to Figure 3-A, the effectiveness of C3b deposition by the classical pathway was the same in all pHs tested, with no difference when compared to the results obtained at standard conditions i.e. at pH 7.4 (n = 3).
Our results show more differences in plasma derived C activation capacity between patients with UC and CD, which is in concordance with the overall immune activation as indicated by CRP, orosomucoid and leucocyte count, and by the fact that CRP may activate C by initiating the classical pathway [ 23].
Both BV and BR ameliorate complement-mediated hemolysis by inhibiting the classical pathway of complement activation at the C1 step via physically interacting with complement proteins [15,16].
MPGN Type 1 is caused by activation of the classical pathway by immune complex formation, and C3 GN results from abnormalities in the alternative pathway of complement.
Upon stimulation of cell proliferation, cytoplasmic nucleolin is translocated via small vesicles to the surface through a temperature-dependent but unconventional secretory pathway, since such an active translocation is not affected by inhibitors of the classical pathway for secretion through the endoplasmic reticulum and Golgi apparatus [6].
Ply prevents complement deposition on S. pneumoniae, mainly by interfering with the classical pathway (Yuste et al. 2005).
