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The 95% CI obtained by the bootstrap technique are also included.
The reliability of the clustering was assessed by the Bootstrap technique.
The standard errors of the estimates of economic costs of MTO were derived by the bootstrap technique which uses a large number of randomly drawn resamples of size ' n' from the original sample to estimate the standard error.
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Finally for the demographic method 3000 individuals were used, ranging from ages 1 to 7. For the direct method, 1318 individuals were used, from ages 2 to 5. For demographic methods, it has been established that a minimum number of 50 individuals is necessary by age and cohort for calculating PMRNs and to estimate confidence intervals by means the bootstrap technique (Barot et al. 2004).
Confidence intervals for the incremental cost effectiveness ratio were also computed by using the bootstrap technique.
Harrell's concordance index (c-index) was used for quantifying the nomogram accuracy, and internal validation was performed on 200 samples by the bootstrapping technique (Bradley and Tibshirani, 1993; Harrell et al, 1996).
The bootstrap technique described in section 'Retrospective and bootstrap analysis' is used to generate 10,000 possible total annual insolation sequences.
E[ p] is the expected value of p using the bootstrap technique for 100 000 bootstraps.
To validate the results, the bootstrap technique was used [ 19].
The predicted distributions needed to be randomly sampled using the bootstrap technique in silico which created a bootstrap population.
Then, 5000 estimates of costs, LY, QALYs, and incremental cost per QALYs were obtained by applying the bootstrapping technique.
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