Sentence examples for by the average methylation from inspiring English sources

To investigate this hypothesis we plotted the absolute difference between the highest and lowest possible methylation estimate for the methylated samples divided by the average methylation estimate against the age of the samples for each gene.

This hypothesis is borne out by the average methylation being higher in the black clade, containing the largest number, most conserved, and likely oldest, elements.

This was evident not only by the average methylation ratios of individual genome compartments, but also in comparisons of the global methylation landscapes.

Below the heat maps, the average of the methylation of all sequences and all CpG sites are given followed by the average methylation entropy.

We hypothesize that if CpG "traffic lights" are not induced by the average methylation of a silent promoter, they may affect TF binding sites (TFBSs) and therefore may regulate transcription.

Basically, we derived the equations of DNA methylation mutation parameter θ m estimated by the average methylation state difference per site (π m ) and by proportion of methylation segregation sites (s m ).

The average methylation per case was calculated by averaging the average methylation per sample for methylated samples for that case.

Global methylation levels were calculated by taking the average methylation level across CpGs per genetic and epigenetic location.

MeDIP-on-Chip data were merged with gene expression microarray data by calculating the average methylation differences within 2 kb windows centered on TSSs of genes that had 5 or more MeDIP-on-Chip probes within the 2 kb window.

By considering the average methylation of all 51 CpGs, methylation was higher in tumor than in normal tissue in 15/20 (75%) cases (pairwise t-test, P = 0.01); of the remaining 5 cases, 2 cases had similar methylation level in normal and tumor (cases 1 and 9), while 3 cases had normal showing higher methylation than tumor (cases 2, 6, 16).

The methylation level of nonsequenced residues was calculated by extrapolation of the average methylation levels of sequenced CpGs of the same promoter.