Sentence examples for by the automatic annotation from inspiring English sources
In Vitis vinifera, for example, integration of RNA-Seq data on the corresponding genomic sequence led to the identification of several genes that had been missed by the automatic annotation procedure in a genome that is already very well annotated [ 12].
Intergenic regions were checked for ORFs missed by the automatic annotation using the BLAST programs [ 46].
This region corresponded to 948 kb on chromosome 18 (upper part of scaffold 122; Figure 1) where 100 predicted genes were proposed by the automatic annotation.
To account for sequences that were present in the genome, but not identified by the automatic annotation, the amino acid sequence of each gene was aligned against every nucleotide contig from all twelve genomes.
In some cases the model as provided by the automatic annotation was adjusted manually, especially if the start- or stop codon was missing or the protein model differed significantly from orthologues in other fungi.
The real challenge is represented by the automatic annotation and/or integration of biological data in real-time, since the objective to reach is to understand them and to achieve the most important goal in bioinformatics: mining information.
By examination of the gene structures and prediction based on the knowledge of other plant GH1 genes, we rectified any errors in gene structures from the automatic annotation by the Rice Genome Sequencing Project contigs.
The automatic annotation performed by Blast2GO was manually revised to guarantee accurate assignment.
In this study, we established a MAP database by combining extensive manually curation with the automatic annotation pipeline.
All these data show great similarity to published results for T. aestivum and H. vulgare, reflecting the accuracy of the automatic annotation provided by dbWFA.
In addition to the annotations described above, we used the Automatic Annotation Server provided by the Kyoto Encyclopedia of Genes and Genomes (KEGG) for all UniSeqs using the single-directional best-hit option.
