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KRT19 was reported as a biomarker for tumor growth or metastasis in HCC; however, the detailed pathway involved by the abnormal expression of KRT19 still remained unclear.
Cancer metastasis is a complicated process facilitated by the abnormal expression of metastasis-related genes, such as those involved in cell proliferation, apoptosis and migration.
Abnormal glucose metabolism in the UE is also evidenced by the abnormal expression of enzymes involved in the PPP: G6PD, the enzyme responsible for the first and rate-limiting step of PPP, is strongly activated in the UE (Fig. 4).
A key change that occurs during EMT is the "cadherin switch", in which the normal expression of E-cadherin is replaced by the abnormal expression of N- or P-cadherin [ 16, 17].
A key change that occurs during EMT is the "cadherin switch", in which the normal expression of E-cadherin is replaced by the abnormal expression of N-cadherin [ 16, 17].
RNA interference (RNAi) is now commonly used to investigate cellular or molecular mechanisms, and the pharmaceutical industry has recognized RNAi as a powerful therapeutic tool for the treatment of both viral infections and diseases caused by the abnormal expression of certain genes [ 12].
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Taken together, it suggests that SOX-9 may be an OA disease candidate gene and that PC exerts its disease modifying activity on OA in part by reversing the abnormal expression of SOX-9 in OA menisci or cartilage.
The high level of ileal colonization in CD patients by AIEC is linked to the abnormal expression of the glycoprotein CEACAM6 which acts as a receptor for AIEC adhesion via type 1 pili [23], [24].
It indicates that hearing loss caused by ILDR1 deficiency might be through the abnormal expression of tricellulin.
Cytokines, such as interferon gamma (IFN-gamma), induce the abnormal expression of microglia by TNF alpha and facilitate the CNS neural immune cascade reaction [ 20].
The abnormal expression of miRNA is involved in tumor proliferation and invasion by inhibiting their target genes (Zhang and Ma, 2012; Zhang et al., 2014b).
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by the abnormal migration
by the abnormal accumulation
by the abnormal tissue
by the abnormal activation
by the abnormal dendritic
by the abnormal depth
by the abnormal muscle
by the abnormal breaking
by the abnormal gelation
by the abnormal cytokine
by the following expression
by the abnormal expansion
by the abnormal presence
by the abnormal oculogram
by the abnormal function
by the abnormal maturation
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