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Lastly, we demonstrated the generality of our SNP sensor by testing its discrimination ability against SM targets containing different single-base mismatches (C C (3), C T (7), and C A (8)) at the 5′ abasic site.
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The selective shR-P16 was further studied by testing whether enhanced discrimination was possible by incorporating further modifications within this shRNA guide strand, including shifting the position of the secondary mismatch and the inclusion of additional mismatches (Figure S2A).
Finally, we conducted analyses to determine the discrimination characteristics of the tool and tested its validity and robustness.
We then tested its potential in the context of primer universality and species discrimination power on a set of previously unidentified gametophyte samples originating from Dutch spore banks.
We obtained similar results (not reported) by testing each form of perceived discrimination against the group which did not experience any type of discrimination.
Because adult fish can easily do this discrimination [12], [30], [37], in the present experiment we investigated the development of large quantity discrimination by testing fish at three different ages (1-, 20- or 40-day-old).
Olfactory discrimination performance was assessed by testing the animals' ability to distinguish between a given odorant used as the S+, and an alternative odorant used as the S–.
Each metric was weighted by its discrimination efficiency.
We have tested visual discrimination and its reversal tasks using this apparatus and confirmed its efficacy.
Between April 2011 and October 2012, Westchester Residential Opportunities Inc. – a private fair housing group -- sent trained testers into communities targeted by the settlement to test for discrimination by real estate agents and landlords based on race or national origin.
The authors probe this systematically by making pairs of mixtures with N components of which M are unshared, and testing those for discrimination by human subjects.
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