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The next challenge is to overcome these limitations by testing a larger number of patients, with more severe forms of ARDS, and for a longer study period.
The aim of the present study was to systematically determine the predictive value of the assay by testing a larger number of clinically used compounds with characterized hERG-inhibitory activity and proarrhythmic potential in humans [ 31] and randomly picked NCEs as well as underlying mechanisms.
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Probabilistic assessment by testing a large number of specimens can be very costly.
By testing a large number of ligands, they were able to establish a verbal characterization of preferred I7 ligands in terms of functional groups and carbon chain length and rigidity.
Cerato and Lutenegger (2007) further evaluated the trend of decreasing N γ with increasing footing width by testing a large range of model-scale square and circular footing sizes, ranging in width from 0.025 to 0.914 m, on two well-graded sands at three relative densities.
We addressed this point by testing a large set of hypothetical values for virus inactivation rate in water (from 7 to 207 days, [29], [30]).
Finally, by testing a large collection of full length 16S sequences, we find at least eight different representative species in the genus Akkermansia.
We extended these findings by testing a large panel of polarized T cell clones at a fixed ratio of T cells to fibroblasts of 10 1.
Concentrations of ESAT-6, Erp and Ag85B were defined by testing a large dilution series of antigen concentrations in a population of tuberculosis patients (n = 12) and the optimal concentration of each antigen was selected.
We assayed alternative population genetic outcomes in the wild by testing a large set of species-specific, mapped molecular markers for deviations from Hardy-Weinberg expectations (HWE), linkage disequilibria (LD), and heterogeneity in the frequencies of introduced alleles.
By testing a large sample of participants from 7 through to 37 years, we showed that the behavioral and neural basis for 3 basic aspects of face perception follows differential developmental trajectories, and that these can be partially attributed to underlying structural brain development that extends well into the third decade of life.
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