Sentence examples for by targeting a defined from inspiring English sources

By targeting a defined region of cDNAs, the DGETP method can generate wider transcriptome coverage together with a higher number of cDNA tags per gene, leading to more precise gene transcription data.

Computational simulations is increasingly facilitating rational design of small molecules that can inhibit or stimulate the biological activity of specific proteins, mostly by targeting a clearly defined binding pocket.

All encode a Vpr that induces host G2/M cell-cycle arrest (Berger et al., 2015), probably by targeting a still poorly defined host cell protein for degradation through the proteasomal pathway or through interaction with proteins of the DNA damage pathway (Laguette et al., 2014).

New York City, she argued, had "adopted a policy of indirect racial profiling by targeting racially defined groups for stops based on local crime suspect data".

"The city adopted a policy of indirect racial profiling by targeting racially defined groups for stops based on local crime suspect data," she wrote.

Agents that can inhibit or reverse these changes by targeting molecularly defined pathways should receive increased attention as novel candidates for oral cancer prevention and therapy [ 2, 3].

While passive immunotherapies often engage the immune system independent of the knowledge of defined tumor antigens (an exception being some forms of adoptive cell therapy ), vaccines elicit specific immune responses by targeting defined tumor antigens.

A related issue is time frame: can the change targeted be achieved by a defined but time-limited intervention, or will it require a longer-lasting program that includes a greater investment in patient engagement, intervention, and support?

Our aim here was to demonstrate the feasibility of editing a plant genome by precisely modifying a defined target DNA motif.

The aim of this study was to demonstrate the feasibility of editing the barley genome by precisely modifying a defined target DNA sequence resulting in a predicted alteration of gene function.

These materials grow and remodel in a process that is governed by a target state defined by a homeostatic radius and a homeostatic material composition.