Sentence examples for by targeted modification of from inspiring English sources
Specific health care products exhibiting a particular rheological behaviour at very high protein content, for example, can only be realised by targeted modification of their supra-molecular structure.
Signaling by these reactive molecules is achieved mainly by targeted modifications of specific residues in proteins (25).
Modern genome engineering technologies have made the targeted modification of human genes possible for a multitude of therapeutic applications.
We find that targeted modification of single parameters suffices to alter the response type.
Recent advances in the targeted modification of complex eukaryotic genomes have unlocked a new era of genome engineering.
In a similar manner, the user can predict the ZFP binding sites for targeted modification of plant and mammalian genomes.
Finally, exome sequencing of cells with targeted modifications of the dystrophin locus showed no TALEN-mediated off-target changes to the protein-coding regions of the genome, as predicted by in silico target site analysis.
Yellow boxes represent the targeted modifications of the genes and the location of terminators.
A brief investigation on the structure activity relationships (SAR) revealed that the targeted modification by a C7 hydroxyl was optimum compared with that of a C4 hydroxyl and that the coupling chain length was crucial for the nematicidal activity.
A series of novel coumarin derivatives were rationally designed and synthesized by use of a complex catalytic system for a targeted modification at the above sites.
Further improvements proliferation and survival of MSCs by formulation optimization of the different additives and improvement targeting efficiency by optimization of the targeting conditions may help to get more MSCs with targeted modification.
