Sentence examples for by targeted expression of from inspiring English sources
Class-specific inhibition of Gq-mediated signaling was produced in the hearts of transgenic mice by targeted expression of a carboxyl-terminal peptide of the α subunit Gαq.
A murine model of neuroblastoma has been established by targeted expression of the human MYCN oncogene in neuroectodermal cells under the control of rat tyrosine hydroxylase promoter (TH-MYCN) [3].
(C ) Blocking exocytosis from URX by targeted expression of tetanus toxin strongly reduces expression of pflp-11 GFP pflp-11 GFP
(E ) Blocking exocytosis from RMG by targeted expression of a tetanus toxin strongly reduces expression of pflp-5::GFP in RMG.
These changes in dendritic and axonal innervation patterns were reversed by targeted expression of the full-length otd coding sequence in mutant neuroblast clones using the Tub-Gal4.
When CC was disrupted structurally by either gene mutations or by targeted expression of tetanus toxin, walking Ve was greatly reduced (Martin et al. 1999; Strauss & Heisenberg 1993).
Moreover, the obesity observed in Sh2b1-null mice was reversed by the targeted expression of Sh2b1 in neurons [ 37].
A link between grm1 overexpression and the development of hereditary melanoma was demonstrated by the targeted expression of murine grm1 cDNA under a melanocyte-specific promotor (dopachrome tautomerase; DCT) [ 23].
These different populations of OPCs are functionally redundant: When any one of them is destroyed at source by the targeted expression of a toxin gene in mice, the remaining cells spread into the vacant territory and restore the normal distribution of OPCs.
We also reviewed recombinant proteins that have been produced by targeted expression in the mammary glands of rabbits and discussed the limitations of transgenic animal bioreactors.
Importantly, Hirota et al. found that cytoplasmic Trx1 suppressed NF-κB activation by UV irradiation, whereas targeted expression of Trx1 in nuclei enhanced NF-κB activity by increasing DNA binding [5].
