Sentence examples for by targeted assembly of from inspiring English sources

Köker, T. et al. Cellular imaging by targeted assembly of hot-spot SERS and photoacoustic nanoprobes using split-fluorescent protein scaffolds.

We set out to determine the human-HPV fusion site by targeted assembly of these RNA-seq reads.

Therefore, we have developed a computational pipeline that derives HLA allele predictions by targeted assembly of shotgun sequence data and comparison to a database of reference allele sequences.

Further, we show that by targeted assembly it is possible to identify tumour-associated fusion transcripts and, finally, we demonstrate the utility of targeted assembly for identifying genome variations in ancient human DNA and large-scale human whole-genome sequencing projects.

PRICE was designed to facilitate this transition by enabling convenient targeted assembly of metagenomic subcomponents of interest.

As it performs a de novo assembly of reads outside the target region, it may be used for the targeted assembly of chimaeric reads whose bases may help characterize novel fusion, translocation or integration events.

In terms of algorithmic efficiency, the strategy for targeted assembly of metagenomic components that was implemented by PRICE scales differently vs. whole-genome assembly algorithms.

For example, the targeted assembly of a series of large spherical structures containing up to 30 palladium ions coordinated by up to 60 bent organic ligands11,12,13,14,15,16 was achieved by considering their topologies17.

This assembly therefore also tested the ability of PRICE to ignore a large amount of irrelevant genomic data when performing a targeted assembly of a large viral genome.

An alternative application for PRICE was the targeted assembly of genomic regions of interest from single-species datasets.

These include the sequencing of novel viral genomes from metagenomic datasets and the targeted assembly of genes-of-interest from whole-genome datasets.