Sentence examples for by systemic blockade of from inspiring English sources

The cellularity of lymph nodes in adult mice was reduced by systemic blockade of lymphotoxin-β receptor (LTβR) signaling with a soluble decoy receptor both in resting and reactive settings.

Although it can be argued that 90% of NR1 knockout in CA3 cells of the forebrain knockout mice may still leave residual amount of cells for pattern completion during recall, the systemic blockade of NMDA receptor function by CPP also did not affect partial cue-initiated pattern completion.

Intragraft expression of IL-15 is elevated during acute rejection in patients and in mice, and systemic blockade of IL-15 in mice prolongs allograft survival.

Certainly other groups have recently reported a reduction in intimal plaque after local [43] or systemic blockade of Ccr2 in vein graft transplants [44].

Systemic blockade of infection-induced DNA hypomethylation countermanded infection-induced behavioral change, thus suggesting necessity.

Systemic blockade of IL-17A also inhibited the allergen-induced accumulation of neutrophils in the airway [ 23].

However, the continuous and systemic blockade of a cytokine results in unwanted side effects, such as increased infections.

Indeed, systemic blockade of C5a reduced lipopolysaccharide-induced neuronal activation in the paraventricular nuclei and amygdala [ 5].

Systemic blockade of TNF reduced activation of p38MAPKα and ERK, whereas inhibition of IL-1 only affected p38MAPKα and blockade of RANK ligand did not result in any decrease in MAPK activation in the synovial membrane.

In addition, the effects of systemic blockade of TNF, IL-1 and receptor activator of nuclear factor-κB (RANK) ligand on the activation of MAPKs were assessed.

Intravitreal injection permits antiangiogenic drugs to effectively reach the retina and theoretically overcomes the problem of the systemic blockade of angiogenesis.