Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs.
Vessels were visualized by systemic administration of fluorescent tracers via tail vein cannulation.
Soutschek, J. et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs.
Liu, F., Song, Y. K. & Liu, D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.
Intra-accumbens administration of AM630 also blocked the reduction in cocaine self-administration and extracellular dopamine produced by systemic administration of JWH133.
Magnetic drug delivery is a promising method to target a drug to a diseased area while reducing negative side effects caused by systemic administration of drugs.
Thus, galanin given i.c.v., 10 min or 2 h prior training, attenuated the impairment of passive avoidance caused by systemic administration of the preferential 5-HT1A receptor agonist 8-OH-DPAT (Misane et al. 1998; Razani et al. 2001).
As DREADDs can be expressed ectopically in specific cell populations and activated by systemic administration of CNO, they enable neuromodulation with simultaneous cell-type specificity and anatomic specificity that is reversible and externally titratable.
To this end, we investigated absence specific spike wave discharge (SWD) susceptibility in control and Cav2.3-deficient mice by systemic administration of γ-hydroxybutyrolactone (GBL, 70 mg/kg i.p ., followed by electrocorticographic radiotelemetric recordings, behavioral analysis and histomorphological characterization.
The present study was designed to examine whether brain inflammation caused by systemic administration of lipopolysaccharides (LPS) alters the expression/processing of amyloid precursor protein (APP) and increases the generation of amyloid β peptide (Aβ).
Apolipoprotein E-deficient mice created by systemic administration of antisense oligodeoxynucleotides: a new model for lipoprotein metabolism studies.
