Sentence examples for by systemic activation of from inspiring English sources

Indeed, the incidence of venous thromboembolism caused by systemic activation of clotting-fibrinolytic system in musculoskeletal sarcoma patients is considerably high [ 2- 5].

H. hepaticus-induced innate immune typhlocolitis is accompanied by systemic activation of the innate immune system 39 and this was also unaffected by TLR2 genotype, as infected 129.RAG−/−.TLR2−/− mice had similar degrees of splenomegaly and granulocyte accumulation as infected 129.RAG−/−.TLR2+/+ littermates (Fig. 3B).

Septic shock, the leading cause of intensive care unit mortality, is caused by systemic activation of the inflammatory cascade.

GNS and ALI are also characterized by systemic activation of the acute phase response with elevation of acute phase proteins in serum [ 9] and epithelial lining fluid [ 10].

Trauma and surgery are known to generate a systemic inflammatory response, characterized by systemic activation of fibrinolysis, coagulation, complement, platelets, and oxidative pathways [ 3, 4].

The improved survival in SR/CR mice co-injected with S180 or CFAF could be the consequence of two distinct events; higher infiltration of SR/CR leukocytes or improved effector function by systemic activation of SR/CR leukocytes induced by S180 coinjection.

It is characterized by a systemic activation of the blood coagulation system, which results in the generation and deposition of fibrin, leading to micro-vascular thrombi and contributing to the development of multi-organ failure.

The pNGAL can be high because of its release into the bloodstream by the systemic activation of neutrophils due to sepsis.

Disseminated intravascular coagulation (DIC) is a syndrome characterized by the systemic activation of blood coagulation which generates intravascular fibrin leading to thrombosis in small and medium sized vessels and eventually organ dysfunction [ 1].

A correlation between presepsin and inflammatory biomarkers, such as CRP, WBC, IL-6 and PCT, can be explained by the ongoing systemic activation of inflammatory biomarkers during severe sepsis and septic shock [ 3, 24].

We used murine antigen-induced arthritis (AIA), as a Th1-mediated experimental arthritis model [ 19], which is characterized by local and systemic activation of macrophages, [ 20] as well as synovial fibroblasts [ 21].