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The review depict that the problem of MDR can be circumvent by synchronized activation of immunogenic cell death pathways that utilize the components of a host's immune system to kill cancer cells in combination with other conventional strategies.
CMAP is produced by synchronized activation of the muscle fibers after axonal innervations, which is the sum of the responses of the striated muscles to stimuli.
SWR network patterns, manifested as negative potentials (sharp waves) in the CA1 stratum radiatum, are triggered by synchronized activation of CA3 pyramidal cells (Buzsaki, 1986; Csicsvari et al., 2000).
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Recent neurological research hypothesizes that the CNS incorporates a library of motor activation modules in order to exert specific and common motor tasks by contributing to the synchronized activation of different muscles.
In normal bipolar mitosis, the activation of the anaphase promoting complex after complete metaphase alignment leads to synchronized activation of separase by degradation of securin, followed by proteolytic cleavage of cohesin, which triggers concerted sister chromosome separation at the metaphase-anaphase transition.
The synchronized activation of SOS genes is mediated by the transcriptional repressor LexA [ 3].
The heart generates and propagates action potentials through synchronized activation of ion channels allowing inward Na+ and Ca2+ and outward K+ currents.
In contrast, we found that synchronized activation of all the climbing fibers within the microcomplex evoked strong rebounds, which could suggest a role in vivo in association with climbing fiber activation.
This will ultimately result in synchronized activation of their target areas.
The spike raster for the IF IF network in Supplementary Figure S8B also reveals that in well synchronized cycles, a robust synchronous volley of the excitatory population is followed by a strong and synchronous activation of inhibitory neurons, the firing of the latter being clearly delayed.
Control over cellular delivery of different functionalities and their synchronized activation is a challenging task.
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