Sentence examples for by suppressing the induction from inspiring English sources

The results of the present study indicate that DEC alleviates alcoholic liver injury, in part by the inhibiting activation of NF-κB and by suppressing the induction of NF-κB-dependent genes.

Of note, the ability of MSC to inhibit the production of the cytokines IL-12p70 and IFN-γ suggest that MSC might be able to suppress inflammation not only by inhibiting the production of pro-inflammatory cytokines during the early step of the inflammatory process, but also by suppressing the induction of Th1 responses which are mainly dependent on IL-12p70 and IFN-γ.

Thus, these results collectively suggest that WEAO inhibits RANKL-induced NFATc1 expression by suppressing the induction of its up-stream activator c-Fos as well as the down-regulation of its negative regulators, Id2 and MafB, thereby inhibiting osteoclastogenesis.

Instead, it is hypothesized that aspirin may reduce the metastatic spread by acting through platelet-mediated mechanisms; indeed, permanent inactivation of platelet COX-1 may play a key role in preventing colorectal adenoma formation, by suppressing the induction of COX-2 expression in adjacent cells [ 3, 65].

Nuclear factor- κB is constitutively activated in malignant melanoma and other cancers, and is believed to confer resistance to cytotoxic therapies by suppressing the induction of apoptosis (Franco et al, 2001; Wang and Richmond, 2001; Yang and Richmond, 2001; Karin et al, 2002).

By suppressing the report.

However, under these conditions EGF was unable to suppress the induction by progestin of desmoplakin protein in the latter cell line (Fig. 3c).

A possible chemical interaction with NF-κB components is further sustained by the ability of 15d-PGJ2 to suppress the induction of COX-2 in PPARγ-deficient macrophages [ 14].

Notably, depletion of endogenous ERK markedly suppressed the induction of INPP4B by irradiation, as determined by western blotting (Fig. 3C, top) and conventional RT-PCR (Fig. 3C, middle).

Treatment with PAO1, cyanide and CHAO suppressed the induction of epsA by more than 40% (Figure 6B) and yqxM by about 50% (Figure 7B) when compared to the untreated control and cyanide mutants.

Another assay showed that the addition of a Gi protein inhibitor, pertussis toxin (PTX), suppressed the induction of PGE2 by S1P (Fig. 4B).