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Our previous research indicates that CXCL12 rescues neurons exposed to excitotoxic insults by supporting the function of the retinoblastoma protein (Rb), which is known to recruit transcriptional repressors such as histone deacetylase (HDAC) to specific promoters, including the promoter of the NR2B gene.
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The loss of the MetE enzyme, the preferred route during aerobic growth, can be compensated by supporting the MetH function with appropriate amounts of cobalamin.
The treatment with Hepa Wash may have improved survival by supporting the detoxification function of the liver and the kidney, thereby interrupting the vicious cycle of elevated toxin level and the resultant worsening of multiple organ failure.
Despite their destructive functions as destruents, micro-organisms play an important role in living vertebrates by supporting the latter's vital functions.
The results obtained by both methods support the function of subfamily A in ABA responses, and provide insights into the shared and different transcriptional regulation machineries as well as evolutionary divergent patterns of PP2C gene regulatory networks in dicots and monocots.
A better understanding of the mechanisms by which cytokines support the functions of resident cells and circulating bone marrow-derived cell populations has led to the development of a number of therapeutic angiogenesis strategies.
The analyses of putative upstream regulatory elements by two approaches further support the functions of subfamily A in ABA signaling, and provide insights into the shared and different transcriptional regulation machineries in dicots and monocots.
By supporting normal cell functioning, the factors contributing to the development and growth of cancer are decreased.
AtWRKY7, CrWRKY35, and PqWRKY1 are each regulated by jasmonate supporting the possible conserved evolutionary function of these proteins in regulating terpene biosynthesis.
These properties are supported by the function of a variety of natural nanodevices.
D.B.K. was supported by the Function Biomedical Informatics Re-search Network (NIH 1 [U24 U24 RR021992]), the BIRN Coordinating Center (https://www.nitrc.org/projects/birn/; NIH 1 [U24 RR025736-01]) and the Conte Center on Brain Programming in Adolescent Vulnerabilities [1P50MH096889-01A1].
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