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If this suggestion is correct, it suggests a quite specific route by which changes in cognitive flexibility can lead to more adaptive and flexible behavior: by supporting the developmental emergence of regret.
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By actively demethylating DNA, DNA repair supports the developmental establishment as well as the maintenance of DNA methylation landscapes and gene expression patterns.
This simultaneous setup in different countries supported the developmental process by taking into account cross-national consensus on important HRQoL issues.
The results support the developmental model of LT tolerance gene regulation and demonstrate the complex genotype by environment interactions that determine LT adaptation in winter annual cereals.
These results not only support the developmental hourglass model, but also highlight the hierarchical aspect of embryogenesis proposed by von Baer.
That epigenetic changes may be causally contributing to cancers is supported by the developmental loss of IGF-II imprinting being associated with the most common solid cancer in childhood, Wilms' tumours [ 125] and also with the constitutional loss of IGF-II imprinting in Beckwith Wiedemann syndrome being associated with an increased risk of cancer [ 126].
Controls by immunodepletion of the IAA antibody did not show labeling in any cellular structure and developmental stage, supporting the specificity of the immunofluorescence results.
We present evidence supporting the use of zebrafish as a translational platform for therapy in human pancreatic cancer by chemically targeting developmental regulators of exocrine pancreas.
The evidence strongly supports the notion that developmental neurotoxicity may be induced by very low exposure levels, i.e. much below those causing any neurotoxicity in adults.
If confirmed by further empirical evidence, this hypothesis could support the inclusion of a developmental perspective in the DSM classifications of borderline personality disorders.
This accumulation of epigenetic modifications in developmental genes supports the notion that replicative senescence is a developmental process.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com