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Thus, while gene duplication, particularly when accompanied by sufficient sequence divergence provides one of the most obvious of candidates for adaptive divergence between species (Prince and Pickett 2002), selectively neutral explanations may explain gene number differences between species, and these may be proffered as null hypotheses that need to be rejected.
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ITS1 and ITS2 were found to contain distinct regions with sufficient sequence divergence to make them suitable as specific identification target sites.
Hebert et al. found that more than 98% of 13,320 congeneric species pairs, including representatives from 11 phyla, have sufficient sequence divergence to ensure easy identification [20].
The 'absent' genes had a log2 ratio inferior to the cut-off value corresponding to 0% EPP, and can include genes with sufficient sequence divergence.
In addition, a few enzymes which represent key enzymes to several pathways or are well known validated targets in pathogenic bacteria or parasites, whilst still retaining sufficient sequence divergence to potentially be able to be targeted effectively were also included.
Probes with negative log2ratios indicate deletions in the test strain and/or sufficient sequence divergence to result in decreased hybridization in the test channel.
On the basis of these observations we hypothesized that the cattle ULBPs evolved by duplication and sequence divergence to produce a sufficient number and diversity of ULBP molecules to deliver an immune activation signal in the presence of immunogenic peptides.
We first established rates of gain/loss of network interactions by using sequence divergence.
The second model is based on gene duplication followed by rapid sequence divergence [ 11, 12].
For the domesticated period of sorghum, Jiang et al. [ 15] observed that gene expression divergence between two lines was mainly determined by DNA sequence divergence.
In the next section, additional simulations investigate the amount of information, as measured by the sequence divergence, alignment length, and number of taxa, needed to detect divergence points.
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