Sentence examples for by substituting a single from inspiring English sources
We also analyzed the amino acids that are critical for antibody binding by substituting a single amino acid within each epitope.
By substituting a single amino acid (K557R or K617A) as a component of the allosteric binding site in the C-terminal region of human muscle type PFK-M with a residue found in the corresponding site of a fungal enzyme, the inhibitory effect of citrate was attenuated.
CSS mice are made by substituting a single chromosome from a donor inbred strain on the genetic background of a host inbred strain (recipient).
Two words A and B are phonological neighbors if we can derive B from A by adding, deleting, or substituting a single phoneme (or vice versa).
In both studies, placing a negative charge at position 352, by substituting a glutamic acid for R352, reduced the single-channel conductance for inward current (outward Cl− flow) when compared to wt CFTR.
To that end, the undirected graph (G) is modified into a directed energy graph (EG = left( {N, L} right)) by leaving the vertices intact and by substituting each single undirected edge with two directional edges.
For example, stabilization of MHC-peptide complexes by substituting single amino acids in a tumor antigen-derived T cell epitope increased specific T cell responses up to 50-fold [36].
A further 5 fluorescent-labeled full-length ATS variants were produced in an analogous manner by substituting single amino acids for cysteines; these are PFF0010 (G156C), PFB1055c (Q161C), PFC1120c (Q182C), PF08_0103 (H154C), and PFF0845c (H159C).
Thus, a number of discrete cable elements are substituted by a single continuous cable that slides over multiple nodes.
Sequence segments missing in the crystal structures were substituted by a single or multiple beads of the corresponding size.
The other issue of major interest is whether any effect of item number and display area can be substituted by a single variable, density (items per unit area), either as a linear or nonlinear term.
